Researchers have been studying the anti-aging effects of Metformin, a drug commonly used to manage diabetes. Recent studies are looking into how the drug may affect metabolic and cellular function associated with aging-related conditions. Experts are looking particularly at whether Metformin can improve gene expression among older adults with impaired glucose tolerance, compared to that of younger individuals. A clinical trial known as the Targeting Aging with Metformin study has been approved in the U.S. and will perform tests on 3,000 elderly people. Scientists will be observing the impact of the drug to see if it can help prevent aging and related development of onset diseases.