For those who suffer chronic migraine headaches, the quest to find relief can be never ending. So, if you’ve tried other treatments with no luck, it may be time to try Botox. While Botox gained popularity as a wrinkle reducer, it wasn’t long before researchers recognized the potential of Botox for treating medical conditions, too. Depending on the case, it can help reduce the symptoms of migraine headaches including nausea, vomiting, sensitivity to lights, sounds and smells.