Those with knee osteoarthritis often experience pain and difficulty with mobility. Recent studies suggest that dietary intake of glucosamine with chondroitin sulfate may reduce pain, relieve stiffness, and improve function. As part of the study, researchers also evaluated the effectiveness of this supplement compared to an anti-inflammatory drug typically prescribed for the condition called celecoxib. Results after 6 months showed that the glucosamine-chondrotin supplement had comparable effectiveness in treating pain and stiffness while benefiting function for patients with knee osteoarthritis.