While honey and agave nectar are both trendy alternatives for sugar right now, it’s time to dig deeper into which is healthier. They seem to have about the same number of calories, but honey has a much higher GI (glycemic index). However, agave nectar consists of 75-90 percent fructose. To sum it up, it looks like honey is the healthier alternative to its competitor, is anti-viral, anti-bacterial, contains antioxidants and more.