Many people experience frequent or painful headaches without knowing some of the less obvious triggers.

Smoked Meats: Nitrates and nitrites that are typically used in packaged meat products such as deli meat and jerky have been known to trigger headaches for some people who get migraines.

Red Wine and Cheese: The tyramine contained in certain cheeses like cheddar and blue cheese as well as in red wines can bring on headaches because it restricts the blood vessels. Researchers add that the polyphenols in red wine may also restrict serotonin metabolism in the brain.

Dehydration: As water and electrolytes leave the body, blood vessels become narrower in order to conserve water and dehydration triggers pain-sensitive nerves in the head.

Brain Freeze: Almost everyone knows that eating cold or frozen foods too quickly causes brain freeze, but research suggests that it may also trigger headaches for those with sensitive teeth. 

Caffeine Withdrawal: Caffeine can have physiological effects on the vascular system, making vessels constrict or relax at different times. The best way to manage these types of headaches is to slowly reduce caffeine intake.

Researchers have been studying the anti-aging effects of Metformin, a drug commonly used to manage diabetes. Recent studies are looking into how the drug may affect metabolic and cellular function associated with aging-related conditions. Experts are looking particularly at whether Metformin can improve gene expression among older adults with impaired glucose tolerance, compared to that of younger individuals. A clinical trial known as the Targeting Aging with Metformin study has been approved in the U.S. and will perform tests on 3,000 elderly people. Scientists will be observing the impact of the drug to see if it can help prevent aging and related development of onset diseases.